FOLR2 polyclonal (N-term), anti-human, mouse
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In stock
SKU
AC-AP5032a
Catalog Number: AC-AP5032a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24013
Applications: WB, FC, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24013
Applications: WB, FC, IHC-P
Datasheet
Request Information
Background:
FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
Other Names:
Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2
Target/Specificity:
This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids of human FOLR2.
Antigen Region:
18-46
Antigen Type: Synthetic Peptide
Gene Name: FOLR2
Gene ID: 2350
Primary Accession: P14207
NCBI Accession: NP_000794.3;NP_001107006.1;NP_001107007.1;NP_001107008.1
Other Accession: Q05685
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
Other Names:
Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2
Target/Specificity:
This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids of human FOLR2.
Antigen Region:
18-46
Antigen Type: Synthetic Peptide
Gene Name: FOLR2
Gene ID: 2350
Primary Accession: P14207
NCBI Accession: NP_000794.3;NP_001107006.1;NP_001107007.1;NP_001107008.1
Other Accession: Q05685
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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