Formin 2 rabbit polyclonal, anti-human, mouse

Backgroud: This gene is a member of the formin homology protein family. The encoded protein is thought to have essential roles in organization of the actin cytoskeleton and in cell polarity. Mutations in this gene have been associated with mental retardation autosomal recessive 47 (MRT47). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015],PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Sequence of unknown origin in the C-terminal part.,similarity:Belongs to the formin homology family. Cappuccino subfamily.,similarity:Contains 1 FH1 (formin homology 1) domain.,similarity:Contains 1 FH2 (formin homology 2) domain.,tissue specificity:Expressed almost exclusively in the developing and mature central nervous system.,

Synonyms: FMN2, Formin-2

Gene Name: FMN2

Gene ID: 56776

SwissProt ID: Q9NZ56

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.