Fos B polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
FOSB, FBJ murine osteosarcoma viral oncogene homolog B, is a protein that, in humans, is encoded by the FOSB gene. FOSB is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. The FOSB gene is mapped to 19q13.32. Delta FOSB is a truncated splice variant of FOSB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. Delta FosB also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.

Description:
Rabbit IgG polyclonal antibody for Protein fosB (FOSB) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
DKFZp686C0818 antibody, FBJ murine osteosarcoma viral oncogene homolog B antibody, fosB antibody, FOSB_HUMAN antibody, G0/G1 switch regulatory protein 3 antibody, G0S3 antibody, GOS 3 antibody, GOS B antibody, GOS3 antibody, GOSB antibody, MGC42291 antibody, Oncogene FOS B antibody, Oncogene FOSB antibody, Protein fos B antibody, Protein fosB antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Fos B (264-291aa LPFQTSQDAPPNLTASLFTHSEVQVLGD), different from the related mouse sequence by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.