FOSB Polyclonal Antibody

Background:
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
Activator protein 1, AP 1, DKFZp686C0818, FBJ murine osteosarcoma viral oncogene homolog B, fosB, FOSB, G0/G1 switch regulatory protein 3, G0S3, GOS 3, GOS B, GOS3, GOSB, MGC42291, Oncogene FOS B, Oncogene FOSB, Protein fos B, Protein fosB

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse FOSB

Swissprot: P53539,P13346

Calculated MW: 48/36 kDa
Observed MW: 36 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.