FOXN1 polyclonal, anti-human

Background:
Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.

Other Names:
Forkhead box protein N1, Winged-helix transcription factor nude, FOXN1, RONU, WHN

Antigen Types:
Synthetic Peptide

Gene Name:
FOXN1
Gene ID:
8456
Primary Accession: O15353
Other Accession: NP_003584;8456;