FOXO1 Polyclonal Antibody

Background:
Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Signal Transduction

Synonyms:
FKH 1, FKH1, FKHR, Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma), Forkhead box O1, Forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, Forkhead, Drosophila, homolog of, in rhabdomyosarcoma, FoxO transcription factor, foxo1, FOXO1, FOXO1A, OTTHUMP00000018301

Immunogen: Synthesized peptide derived from human FoxO1 around the non-phosphorylation site of Ser319.

Swissprot: Q12778

Calculated MW: 70 kDa
Observed MW: 78 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-9809/sc-9808/sc-12892/sc-34891/sc-34890/sc-34893/sc-11350/sc-67140/sc-49437

Citation(s):
https://pubmed.ncbi.nlm.nih.gov/31999897/