FOXO1A polyclonal, anti-rat, human

Quantity: 100 µg

Background:
Forkhead box protein O1, also known as FKHR or FOXO1A, is a protein that in humans is encoded by the FOXO1 gene. It is mapped to 13q14.11. This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO1 plays important roles in regulation of gluconeogenesis and glycogenolysis by insulin signaling, and is also central to the decision for a preadipocyte to commit to adipogenesis. This gene is primarily regulated through phosphorylation on multiple residues. Its transcriptional activity is dependent on its phosphorylation state. What's more, FOXO1 may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

Description:
Rabbit IgG polyclonal antibody for Forkhead box protein O1 (FOXO1) detection. Tested with WB in Human, Rat.

Synonyms:
FKH 1 antibody, FKH1 antibody, FKHR antibody, Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) antibody, Forkhead box O1 antibody, Forkhead box protein O1 antibody, Forkhead box protein O1A antibody, Forkhead in rhabdomyosarcoma antibody, Forkhead, Drosophila, homolog of, in rhabdomyosarcoma antibody, FoxO transcription factor antibody, foxo1 antibody, FOXO1_HUMAN antibody, FOXO1A antibody, OTTHUMP00000018301 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human FOXO1A recombinant protein (Position: N456-G655). Human FOXO1A shares 93% amino acid (aa) sequence identity with both mouse and rat FOXO1A.E.coli-derived human FOXO1A recombinant protein (Position: N456-G655). Human FOXO1A shares 93% amino acid (aa) sequence identity with both mouse and rat FOXO1A.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.