FoxO3A (phospho-S253) polyclonal, anti-human, mouse
€328.00
In stock
SKU
BS4713
Background:
FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two-tiered mechanism of phosphorylation and acetylation.FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors.
Alternative Name:
Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1, FOXO3, FKHRL1, FOXO3A
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200, IF: 1:50~1:200
Specificity: p-FoxO3A (S253) polyclonal antibody detects endogenous levels of FoxO3A protein when phosphorylated at Ser253.
Immunogen:
Synthetic phosphopeptide derived from human FOXO3A around the phosphorylation site of Serine 253.
MW: ~ 97 kDa
Swis Prot.: O43524
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two-tiered mechanism of phosphorylation and acetylation.FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors.
Alternative Name:
Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1, FOXO3, FKHRL1, FOXO3A
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200, IF: 1:50~1:200
Specificity: p-FoxO3A (S253) polyclonal antibody detects endogenous levels of FoxO3A protein when phosphorylated at Ser253.
Immunogen:
Synthetic phosphopeptide derived from human FOXO3A around the phosphorylation site of Serine 253.
MW: ~ 97 kDa
Swis Prot.: O43524
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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