FOXO4 C-terminal region polyclonal, anti-human, mouse, rat, pig, dog, guinea pig, horse, bovine

Background:
This is a rabbit polyclonal antibody against FOXO4. It was validated on Western Blot by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein.

Other Names:
Forkhead box protein O4, Fork head domain transcription factor AFX1, FOXO4, AFX, AFX1, MLLT7

Target/Specificity:
FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.

Immunogen:
The immunogen for anti-FOXO4 antibody: synthetic peptide directed towards the C terminal of human FOXO4

Gene Name:
FOXO4
Gene Name:
4303
Swissprot ID: P98177
NCBI Accession:
NP_005929
Primary Accession: P98177
Other Accession: P98177;NP_005929;NM_005938
Purification: Affinity Purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.