FOXO4 middle region polyclonal, anti-human, mouse, rat, pig, horse, dog

Background:
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

Other Names:
Forkhead box protein O4, Fork head domain transcription factor AFX1, FOXO4, AFX, AFX1, MLLT7

Immunogen:
The immunogen for anti-FOXO4 antibody: synthetic peptide directed towards the middle region of human FOXO4

Gene Name:
FOXO4
Gene Name:
4303
NCBI Accession:
NP_005929
Primary Accession: P98177
Other Accession: NM_005938;NP_005929
Purification: Affinity Purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.