FOXO4 Polyclonal Antibody

Background:
This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
AFX, AFX1, Afxh, ALL1-fused gene from X chromosome, Fork head domain transcription factor AFX1, Forkhead box O4, Forkhead box protein O4, FOXO 4, Foxo4, FOXO4, MGC117660, MGC120490, Mixed lineage leukemia, translocated to, 7, MLLT7, Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila), translocated to, 7, Myeloid/lymphoid or mixed lineage leukemia, translocated to, 7, RGD1561201

Immunogen: Synthetic peptide of human FOXO4

Swissprot: P98177
Gene Accession: NP005929

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:350, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.