FOXO4 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP21102a
Catalog Number: AC-AP21102a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51188
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51188
Applications: WB
Datasheet
Request Information
Background:
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Other Names:
Forkhead box protein O4, Fork head domain transcription factor AFX1, FOXO4, AFX, AFX1, MLLT7
Target/Specificity:
This FOXO4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 415-450 amino acids from the C-terminal region of human FOXO4.
Gene Name: FOXO4
Gene ID: 4303
Primary Accession: P98177
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Other Names:
Forkhead box protein O4, Fork head domain transcription factor AFX1, FOXO4, AFX, AFX1, MLLT7
Target/Specificity:
This FOXO4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 415-450 amino acids from the C-terminal region of human FOXO4.
Gene Name: FOXO4
Gene ID: 4303
Primary Accession: P98177
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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