FOXO4 rabbit polyclonal, anti-human, mouse, rat

Backgroud: The Forkhead family of transcription factors is involved in tumorigenesis of rhabdomyosarcoma and acute leukemias. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.

Synonyms: FOXO4, AFX, AFX1, MLLT7, Forkhead box protein O4, Fork head domain transcription factor AFX1

Gene Name: FOXO4

Gene ID: 4303

SwissProt ID: P98177

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.