FOXP2 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP5753b
Background:
FOXP2 is a member of the forkhead/winged-helix(FOX) family of transcription factors. It is expressed in fetal andadult brain as well as in several other organs such as the lung andgut. The protein product contains a FOX DNA-binding domain and alarge polyglutamine tract and is an evolutionarily conservedtranscription factor, which may bind directly to approximately 300to 400 gene promoters in the human genome to regulate theexpression of a variety of genes. This gene is required for properdevelopment of speech and language regions of the brain duringembryogenesis, and may be involved in a variety of biologicalpathways and cascades that may ultimately influence languagedevelopment. Mutations in this gene cause speech-language disorder1 (SPCH1), also known as autosomal dominant speech and languagedisorder with orofacial dyspraxia. Multiple alternative transcriptsencoding different isoforms have been identified in this gene.
Other Names:
Forkhead box protein P2, CAG repeat protein 44, Trinucleotide repeat-containing gene 10 protein, FOXP2, CAGH44, TNRC10
Gene Name: FOXP2
Gene ID: 93986
Primary Accession: O15409
Other Accession: NP_055306.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
FOXP2 is a member of the forkhead/winged-helix(FOX) family of transcription factors. It is expressed in fetal andadult brain as well as in several other organs such as the lung andgut. The protein product contains a FOX DNA-binding domain and alarge polyglutamine tract and is an evolutionarily conservedtranscription factor, which may bind directly to approximately 300to 400 gene promoters in the human genome to regulate theexpression of a variety of genes. This gene is required for properdevelopment of speech and language regions of the brain duringembryogenesis, and may be involved in a variety of biologicalpathways and cascades that may ultimately influence languagedevelopment. Mutations in this gene cause speech-language disorder1 (SPCH1), also known as autosomal dominant speech and languagedisorder with orofacial dyspraxia. Multiple alternative transcriptsencoding different isoforms have been identified in this gene.
Other Names:
Forkhead box protein P2, CAG repeat protein 44, Trinucleotide repeat-containing gene 10 protein, FOXP2, CAGH44, TNRC10
Gene Name: FOXP2
Gene ID: 93986
Primary Accession: O15409
Other Accession: NP_055306.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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