FOXP3 (clone MF333F), anti-mouse
€204.00
In stock
SKU
ARP-23-A0025
Catalog Number: 23-A0025
Size: 25 µg
Isotype: Rat IgG2a kappa
Size: 25 µg
Isotype: Rat IgG2a kappa
Decription:
FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.
Synonyms: Forkhead Box Protein P3, Scurfin
Clone: MF333F
Isotype: Rat IgG2a kappa
Immunogen: Recombinant mouse FOXP3.
Reactivity: mouse
Specificity: Recognizes mouse FOXP3. Detects a band of ~46-49kDa by Western blot.
Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Applications:
ELISA: (direct or indirect: 1:2'000-1:10'000)
Immunocytochemistry
Immunohistochemistry
Western blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature).
Working Dilution: Optimal conditions must be determined individually for each application.
Concentration: 1mg/ml
Storage: 2-8C immediate use, or -20C (aliquote)
FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.
Synonyms: Forkhead Box Protein P3, Scurfin
Clone: MF333F
Isotype: Rat IgG2a kappa
Immunogen: Recombinant mouse FOXP3.
Reactivity: mouse
Specificity: Recognizes mouse FOXP3. Detects a band of ~46-49kDa by Western blot.
Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Applications:
ELISA: (direct or indirect: 1:2'000-1:10'000)
Immunocytochemistry
Immunohistochemistry
Western blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature).
Working Dilution: Optimal conditions must be determined individually for each application.
Concentration: 1mg/ml
Storage: 2-8C immediate use, or -20C (aliquote)
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