FPR1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: formyl peptide receptor 1(FPR1) Homo sapiens This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010],function:High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.,PTM:Phosphorylated; which is necessary for desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Neutrophils.,

Synonyms: FPR1, fMet-Leu-Phe receptor, fMLP receptor, N-formyl peptide receptor, FPR, N-formylpeptide chemoattractant receptor

Gene Name: FPR1

Gene ID: 2357

SwissProt ID: P21462

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.