Frizzled 7 polyclonal, anti-human

Background:
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Other Names:
Frizzled-7, Fz-7, hFz7, FzE3, FZD7

Antigen Types:
Synthetic Peptide

Gene Name:
FZD7
Gene ID:
8324
Primary Accession: O75084
Other Accession: NP_003498;8324;14369 (mouse);