Frizzled-7 Polyclonal Antibody

Background:
frizzled class receptor 7(FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008],

Alternative Names:
FZD7, Frizzled-7, Fz-7, hFz7, FzE3

Immunogen: The antiserum was produced against synthesized peptide derived from human FZD7. AA range:45-94

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 64

GeneID: FZD7

Storage: -20°C/1 year

NOTE: For Research Use Only