FANCD2 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP69858
Background:
Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Other Names:
FANCD2; FACD; Fanconi anemia group D2 protein; Protein FACD2
Antigen Type: synthetic peptide
Antigen Type: FANCD2
Gene ID: 2177
Primary Accession: Q9BXW9
Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Other Names:
FANCD2; FACD; Fanconi anemia group D2 protein; Protein FACD2
Antigen Type: synthetic peptide
Antigen Type: FANCD2
Gene ID: 2177
Primary Accession: Q9BXW9
| Is Featured? | No |
|---|
Write Your Own Review