FSBP polyclonal, anti-human, mouse, rat

Background:
Fibrinogen silencer-binding protein, Function: Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1. Subunit structure: Interacts with APBA1 (via PDZ 1 and 2 domains). Subcellular location: Nucleus. Tissue specificity: Expressed in multiple tissues including brain. Miscellaneous: Intragenic, in the second intron of RAB54B gene.

Alternative Name:
Fibrinogen silencer-binding protein

Application Dilution: WB: 1:500~1:1000

Specificity: FSBP polyclonal antibody detects endogenous levels of FSBP protein.

Immunogen:
A synthetic peptide corresponding to residues in Human BFSBP.

MW: ~ 34 kDa

Swis Prot.: O95073

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.