FSCN1 (clone ), anti-human antibody
€305.00
In stock
SKU
AC-ABV11772-50
Catalog Number: AC-ABV11772-50
Size: 50 µl
Host: Mouse IgG
Applications: WB, IF, FC, ICC, E
Datasheet
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Size: 50 µl
Host: Mouse IgG
Applications: WB, IF, FC, ICC, E
Datasheet
Request Information
Background:
FSCN1 is an actin-bundling protein that provides rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. And this protein is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. FSCN1 expression has been localized to neurons, glial cells, and endothelial cells.
Other Names:
FAN1, HSN, SNL
Primary Accession: NP_003079
Concentration (mg/ml): 1 mg/ml
FSCN1 is an actin-bundling protein that provides rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. And this protein is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. FSCN1 expression has been localized to neurons, glial cells, and endothelial cells.
Other Names:
FAN1, HSN, SNL
Primary Accession: NP_003079
Concentration (mg/ml): 1 mg/ml
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