FSCN1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Synonyms: FAN1, HSN, SNL, p55

Cellular Location: Cell junction Cell projection Cytoplasm cytoskeleton cytosol filopodium invadopodium microvillus

Immunogen:
Recombinant protein of human FSCN1

Gene Symbol: FSCN1

Gene ID: 6624

Swiss prot: Q16658

Calculated MW: 55kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.