FTO Polyclonal Antibody

Background:
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Research Area: Cancer, Cardiovascular, Metabolism, Neuroscience

Synonyms:
AlkB homolog 9, ALKBH9, Alpha-ketoglutarate-dependent dioxygenase FTO, AW743446, Fat mass and obesity-associated protein, FATSO, MOUSE, HOMOLOG OF, Fto, FTO, GDFD, KIAA1752, mKIAA1752, Protein fatso

Immunogen: Recombinant protein of human FTO

Swissprot: Q9C0B1
Gene Accession: BC003583

Calculated MW: 58 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-83811/sc-83813/sc-98768