FTO Polyclonal Antibody

Background:
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Research Area: Cancer, Cardiovascular, Metabolism, Neuroscience

Synonyms:
FTO, ALKBH9, BMIQ14, GDFD

Immunogen: Recombinant fusion protein of human FTO (NP_001073901.1).

Swissprot: Q9C0B1
Gene ID: 79068

Calculated MW: 6 kDa/12 kDa/14 kDa/58 kDa
Observed MW: 58 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.