FUS polyclonal, anti-human, mouse

Background:
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Synonyms: TLS, ALS6, ETM4, FUS1, POMP75, HNRNPP2

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human FUS

Gene Symbol: FUS

Gene ID: 2521

Swiss prot: P35637

Calculated MW: 53kDa

Recommended dilution:
IHC 1:10-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.