FUSIP1 polyclonal (C-term), anti-human

FUSIP1 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP17421B
Catalog Number: AC-AP17421B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36992
Applications: WB
Datasheet

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Background:
This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.

Other Names:
Serine/arginine-rich splicing factor 10, 40 kDa SR-repressor protein, SRrp40, FUS-interacting serine-arginine-rich protein 1, Splicing factor SRp38, Splicing factor, arginine/serine-rich 13A, TLS-associated protein with Ser-Arg repeats, TASR, TLS-associated protein with SR repeats, TLS-associated serine-arginine protein, TLS-associated SR protein, SRSF10, FUSIP1, FUSIP2, SFRS13A, TASR

Target/Specificity:
This FUSIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human FUSIP1.

Antigen Region:
197-225

Antigen Type: Synthetic Peptide

Gene Name: SRSF10
Gene ID: 10772
Primary Accession: O75494
NCBI Accession: NP_001177934.1;NP_001177935.1;NP_001177936.1;NP_001177938.1;NP_006616.1;NP_473357.1
Other Accession: Q9R0U0; NP_001177935.1; NP_001177934.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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