FXN / Frataxin Polyclonal Antibody

Background:
This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
FXN, CyaY, FA, FARR, FRDA, X25, frataxin

Immunogen: Recombinant fusion protein of human FXN / Frataxin (NP_000135.2).

Swissprot: Q16595
Gene ID: 2395

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.