FXYD4 Rabbit polyclonal antibody, anti-human, mouse, rat
€0.00
In stock
SKU
BT-AP10103
Catalog Number: BT-AP10103
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Application(s): IHC-p, IF
Datasheet
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Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Application(s): IHC-p, IF
Datasheet
Request Information
Background:
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain| beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4| originally named CHIF for channel-inducing factor| has been shown to modulate the properties of the Na|K-ATPase| as has FXYD2| also known as the gamma subunit of the Na|K-ATPase| and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2)| with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.
Research Area: Signal transduction
Synonyms: FXYD4
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain| beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4| originally named CHIF for channel-inducing factor| has been shown to modulate the properties of the Na|K-ATPase| as has FXYD2| also known as the gamma subunit of the Na|K-ATPase| and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2)| with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.
Research Area: Signal transduction
Synonyms: FXYD4
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
| Is Featured? | No |
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