FYCO1 Polyclonal Antibody

Background:
This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2).

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
CATC2, CTRCT18, DKFZp779K1152, FLJ13335, FYCO1, FYCO1, FYVE and coiled coil domain containing 1, FYVE and coiled coil domain containing protein 1, FYVE and coiled-coil domain-containing protein 1, MGC126517, MGC126519, RUFY3, RUN and FYVE domain containing 3, ZFYVE7, Zinc finger FYVE domain containing protein 7, Zinc finger FYVE domain-containing protein 7

Immunogen: Fusion protein of human FYCO1

Swissprot: Q9BQS8
Gene Accession: BC007218

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.08 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.