FZD8 / frizzled 8 polyclonal, anti-human

Background:
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

Other Names:
Frizzled-8, Fz-8, hFz8, FZD8

Antigen Types:
Synthetic Peptide

Gene Name:
FZD8
Gene ID:
8325
Primary Accession: Q9H461
Other Accession: NP_114072;8325;14370 (mouse);