G-protein coupled receptor 30 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
G-protein coupled estrogen receptor 1(GPER1), also known as the GPR30 or CEPR is a G protein-coupled receptor that in humans is encode d by the GPER gene. This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. It is mapped to 7p22.3. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.

Description:
Rabbit IgG polyclonal antibody for G-protein coupled estrogen receptor 1 (GPER1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
CEPR antibody, Chemoattractant receptor-like 2 antibody, Chemokine receptor-like 2 antibody, CMKRL2 antibody, FEG-1 antibody, Flow-induced endothelial G protein-coupled receptor antibody, Flow-induced endothelial G-protein coupled receptor 1 antibody, G protein-coupled receptor 30 antibody, G-protein coupled estrogen receptor 1 antibody, G-protein coupled receptor 30 antibody, GPCR-Br antibody, Gper antibody, GPER_HUMAN antibody, GPR30 antibody, IL8-related receptor DRY12 antibody, Lergu antibody, LERGU2 antibody, leucine rich protein in GPR30 3'UTR antibody, LYGPR antibody, Lymphocyte-derived G-protein coupled receptor antibody, Membrane estrogen receptor antibody, mER antibody, MGC99678 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human G-protein coupled receptor 30(275-288aa ENVFISVHLLQRTQ), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.