G22P1 antibody (clone 4C2-1A6), anti-human
€435.00
In stock
SKU
AC-AT2136a
Catalog Number: AC-AT2136a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, E
Request Information AC-AT2136a">Request Information
Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Other Names:
X-ray repair cross-complementing protein 6, 364-, 4299-, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1
Antigen Type:
Recombinant Protein
Gene Name: XRCC6
Gene ID: 2547
NCBI Accession: NP_001460.1
Primary Accession: P12956
Other Accession: BC008343
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Other Names:
X-ray repair cross-complementing protein 6, 364-, 4299-, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1
Antigen Type:
Recombinant Protein
Gene Name: XRCC6
Gene ID: 2547
NCBI Accession: NP_001460.1
Primary Accession: P12956
Other Accession: BC008343
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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