G3BP-1 (phospho-S232) polyclonal, anti-human, mouse, rat
€328.00
In stock
SKU
BS4077
Background:
G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alternative Name:
G3BP1, G3BP, hDH VIII, G3BP-1, Ras GTPase-activating protein-binding protein 1, GAP SH3 domain-binding protein 1
Application Dilution: IHC: 1:50~1:200
Specificity: p-G3BP-1 (S232) polyclonal antibody detects endogenous levels of G3BP-1 protein only when phosphorylated at Ser232.
Immunogen:
Synthetic phosphopeptide derived from human G3BP-1 around the phosphorylation site of Serine 232.
MW: ~ 52 kDa
Swis Prot.: Q13283
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alternative Name:
G3BP1, G3BP, hDH VIII, G3BP-1, Ras GTPase-activating protein-binding protein 1, GAP SH3 domain-binding protein 1
Application Dilution: IHC: 1:50~1:200
Specificity: p-G3BP-1 (S232) polyclonal antibody detects endogenous levels of G3BP-1 protein only when phosphorylated at Ser232.
Immunogen:
Synthetic phosphopeptide derived from human G3BP-1 around the phosphorylation site of Serine 232.
MW: ~ 52 kDa
Swis Prot.: Q13283
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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