G3BP1 Polyclonal Antibody

Background:
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
G3BP1, G3BP, HDH-VIII

Immunogen: Recombinant fusion protein of human G3BP1 (NP_938405.1).

Swissprot: Q13283
Gene ID: 10146

Calculated MW: 13 kDa/52 kDa
Observed MW: 68 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.