G3BP1 polyclonal (C-term), anti-human

Background:
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Other Names:
Ras GTPase-activating protein-binding protein 1, G3BP-1, ATP-dependent DNA helicase VIII, hDH VIII, GAP SH3 domain-binding protein 1, G3BP1, G3BP

Target/Specificity:
This G3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the C-terminal region of human G3BP1.

Antigen Region:
401-430

Antigen Type: Synthetic Peptide

Gene Name: G3BP1 {ECO:0000303|PubMed:23279204, ECO:0000312|HGNC:HGNC:30292}
Gene ID: 10146
Primary Accession: Q13283
NCBI Accession: NP_005745.1;NP_938405.1
Other Accession: P97855; Q32LC7; NP_938405.1; NP_005745.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.