G6PC2 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP8684a
Background:
G6PC2 may hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. It may be responsible for glucose production through glycogenolysis and gluconeogenesis. G6PC2 is an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes.
Other Names:
Glucose-6-phosphatase 2, G-6-Pase 2, G6Pase 2, Islet-specific glucose-6-phosphatase catalytic subunit-related protein, G6PC2, IGRP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8684a was selected from the N-term region of human G6PC2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: G6PC2
Gene ID: 57818
Primary Accession: Q9NQR9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
G6PC2 may hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. It may be responsible for glucose production through glycogenolysis and gluconeogenesis. G6PC2 is an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes.
Other Names:
Glucose-6-phosphatase 2, G-6-Pase 2, G6Pase 2, Islet-specific glucose-6-phosphatase catalytic subunit-related protein, G6PC2, IGRP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8684a was selected from the N-term region of human G6PC2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: G6PC2
Gene ID: 57818
Primary Accession: Q9NQR9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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