GAB2 Polyclonal Antibody

Background:
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
GAB 2, Gab2, GAB2, Grb 2 associated binder 2, GRB 2 associated binding protein 2, Grb2 associated binder 2, GRB2 associated binder 2 pp100, GRB2 associated binding protein 2, GRB2-associated binder 2, GRB2-associated-binding protein 2, Growth factor receptor bound protein 2 associated protein 2, Growth factor receptor bound protein 2-associated protein 2, KIAA0571, p97, PH domain containing adaptor molecule p97, pp100

Immunogen: Recombinant protein of human GAB2

Swissprot: Q9UQC2
Gene Accession: BC131711

Calculated MW: 74 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-9313/sc-9311/sc-25498