GABAA Rα1 Polyclonal Antibody

GABAA Rα1 Polyclonal Antibody

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In stock
SKU
ELK-ES4299
Catalog Number: ELK-ES4299
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
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Background:
gamma-aminobutyric acid type A receptor alpha1 subunit(GABRA1) Homo sapiens This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],

Alternative Names:
GABRA1, Gamma-aminobutyric acid receptor subunit alpha-1, GABA(A) receptor subunit alpha-1

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GABRA1. AA range:61-110

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 50

GeneID: GABRA1

Storage: -20°C/1 year

NOTE: For Research Use Only
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