GABAA Rα4 Polyclonal Antibody

Background:
gamma-aminobutyric acid type A receptor alpha4 subunit(GABRA4) Homo sapiens Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011],

Alternative Names:
GABRA4, Gamma-aminobutyric acid receptor subunit alpha-4, GABA(A) receptor subunit alpha-4

Immunogen: The antiserum was produced against synthesized peptide derived from human GABRA4. AA range:81-130

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 60

GeneID: GABRA4

Storage: -20°C/1 year

NOTE: For Research Use Only