GABAA Receptor alpha1 Polyclonal Antibody

Background:
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene

Research Area: Cancer, Neuroscience

Synonyms:
ECA4, EIEE19, EJM, EJM5, Gaba receptor alpha 1 polypeptide, GABA(A) receptor, GABA(A) receptor subunit alpha 1, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABRA 1, GABRA1, Gamma aminobutyric acid (GABA) A receptor alpha 1, Gamma aminobutyric acid A receptor alpha 1, Gamma aminobutyric acid receptor subunit alpha 1, Gamma aminobutyric acid type A receptor alpha1 subunit, Gamma-aminobutyric acid receptor subunit alpha-1, GBRA1

Immunogen: KLH conjugated Synthetic peptide corresponding to mouse GABA A Receptor alpha 1

Swissprot: P14867,P62813,P62812

Calculated MW: 52 kDa
Observed MW: 52 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 0.73 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.