GABAA Receptor beta-3 (Ser408/409) polyclonal, anti-human, mouse, bovine, dog, chicken, Xenopus, zebrafish
€536.00
In stock
SKU
252541
Protein Family: Receptors and Channels
Pathway and Disease: Nervous and Sensory Systems
Description:
Gamma-aminobutyric acid receptor subunit beta-3 (GABAA Receptor, b3) is a receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. The GABA receptor is pentameric in structure, and there are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Phosphorylation of serine 408 and serine 409 within the beta-3 subunit have been shown to be critical for the functional modulation of beta-3 containing recombinant receptors.
Alternate Names: Gamma-aminobutyric acid receptor subunit beta-3, GABA(A) receptor subunit beta-3, Gabrb3, Gabrb-3
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: P63079
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser408/409 of rat GAGAA receptor, b3.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems
Description:
Gamma-aminobutyric acid receptor subunit beta-3 (GABAA Receptor, b3) is a receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. The GABA receptor is pentameric in structure, and there are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Phosphorylation of serine 408 and serine 409 within the beta-3 subunit have been shown to be critical for the functional modulation of beta-3 containing recombinant receptors.
Alternate Names: Gamma-aminobutyric acid receptor subunit beta-3, GABA(A) receptor subunit beta-3, Gabrb3, Gabrb-3
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: P63079
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser408/409 of rat GAGAA receptor, b3.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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