GABARAP polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7642
Background:
In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton. The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex.
Alternative Name:
ATG8A, FLC 3B, FLC3B, FLJ25768, GABA(A) receptor associated protein, GABA(A) receptor-associated protein, GABARAP a, GABARAP, Gamma aminobutyric acid receptor associated protein, Gamma-aminobutyric acid receptor-associated protein, GBRAP_HUMAN, MGC120154, MGC120155, MM 46, MM46,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: GABARAP polyclonal antibody detects endogenous levels of GABARAP protein.
Immunogen:
Recombinant full length Human GABARAP.
MW: ~13 kDa
Swis Prot.: O95166
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton. The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex.
Alternative Name:
ATG8A, FLC 3B, FLC3B, FLJ25768, GABA(A) receptor associated protein, GABA(A) receptor-associated protein, GABARAP a, GABARAP, Gamma aminobutyric acid receptor associated protein, Gamma-aminobutyric acid receptor-associated protein, GBRAP_HUMAN, MGC120154, MGC120155, MM 46, MM46,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: GABARAP polyclonal antibody detects endogenous levels of GABARAP protein.
Immunogen:
Recombinant full length Human GABARAP.
MW: ~13 kDa
Swis Prot.: O95166
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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