GABARAP polyclonal, anti-human, mouse, rat

Background:
In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton. The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex.

Alternative Name:
GABARAP, FLC3B, HT004, ATG8A, FLC 3B, FLC3B, FLJ25768, GABA type A receptor associated protein, GABA(A) receptor associated protein, GABA(A) receptor-associated protein, GABARAP a, GABARAP, Gamma aminobutyric acid receptor associated protein, Gamma-aminobutyric acid receptor-associated protein, GBRAP, MGC120154, MGC120155, MM 46, MM46,

Application Dilution:
WB:1:500
IHC:1:50-1:200
FC:1:50-1:100

Specificity: GABARAP polyclonal antibody detects endogenous levels of GABARAP protein.

Immunogen:
Recombinant protein

MW: 14 kDa

Swiss-Prot: O95166(Human) Q8R3R8(Mouse) P60517(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.