GABARAPL1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70920
Background:
GABARAPL1 (γ-aminobutyric acid receptor-associated protein-like 1), also known as ATG8, GEC1 (glandular epithelial cell protein 1), APG8L, ATG8L or APG8-LIKE, is a 117 amino acid protein belonging to the MAP1 LC3 family. Localized to the endoplasmic reticulum and Golgi apparatus, GABARAPL1 is ubiquitously expressed. Very high levels of GABARAPL1 are found in brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. GABARAPL1 increases cell-surface expression of κ-type opioid receptor (KOR) through facilitating anterograde intracellular trafficking of the receptor. GABARAPL1 may have chaperone-like effects for many cell surface proteins along the biosynthesis pathway and may regulate the trafficking of receptor GABA. GABARAPL1 interacts with GABAA Rγ2, β Tubulin and KOR-1.
Alternative Name:
ATG8, GEC1, APG8L, ATG8B, ATG8L, APG8-LIKE,
Application Dilution: WB: 1:500 - 1:2000
Specificity: GABARAPL1 polyclonal antibody detects endogenous levels of GABARAPL1 protein.
Immunogen:
Recombinant protein of human GABARAPL1.
MW: ~ 14 kDa
Swis Prot.: Q9H0R8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
GABARAPL1 (γ-aminobutyric acid receptor-associated protein-like 1), also known as ATG8, GEC1 (glandular epithelial cell protein 1), APG8L, ATG8L or APG8-LIKE, is a 117 amino acid protein belonging to the MAP1 LC3 family. Localized to the endoplasmic reticulum and Golgi apparatus, GABARAPL1 is ubiquitously expressed. Very high levels of GABARAPL1 are found in brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. GABARAPL1 increases cell-surface expression of κ-type opioid receptor (KOR) through facilitating anterograde intracellular trafficking of the receptor. GABARAPL1 may have chaperone-like effects for many cell surface proteins along the biosynthesis pathway and may regulate the trafficking of receptor GABA. GABARAPL1 interacts with GABAA Rγ2, β Tubulin and KOR-1.
Alternative Name:
ATG8, GEC1, APG8L, ATG8B, ATG8L, APG8-LIKE,
Application Dilution: WB: 1:500 - 1:2000
Specificity: GABARAPL1 polyclonal antibody detects endogenous levels of GABARAPL1 protein.
Immunogen:
Recombinant protein of human GABARAPL1.
MW: ~ 14 kDa
Swis Prot.: Q9H0R8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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