GABBR1 antibody (clone 2D7), anti-human
€435.00
In stock
SKU
AC-AT2138a
Catalog Number: AC-AT2138a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
Request Information AC-AT2138a">Request Information
Background:
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants.
Other Names:
Gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, GABBR1, GPRC3A
Antigen Type:
Recombinant Protein
Gene Name: GABBR1
Gene ID: 2550
NCBI Accession: NP_001461.1;NP_068703.1;NP_068704.2
Primary Accession: Q9UBS5
Other Accession: BC050532
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants.
Other Names:
Gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, GABBR1, GPRC3A
Antigen Type:
Recombinant Protein
Gene Name: GABBR1
Gene ID: 2550
NCBI Accession: NP_001461.1;NP_068703.1;NP_068704.2
Primary Accession: Q9UBS5
Other Accession: BC050532
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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