GABBR2 Polyclonal Antibody

Background:
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.

Research Area: Cancer, Neuroscience

Synonyms:
GABBR2, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099

Immunogen: Recombinant fusion protein of human GABBR2 (NP_005449.5).

Swissprot: O75899
Gene ID: 9568

Calculated MW: 105 kDa
Observed MW: 122 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.