GABPA (clone 8C1B10), anti-human, mouse

Background:
GABPA: GA binding protein transcription factor, alpha subunit 60kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: NFT2, NRF2

Immunogen: Purified recombinant fragment of human GABPA (aa120-190) expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage