GABRB3 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. And this gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. It may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Description:
Rabbit IgG polyclonal antibody for Gamma-aminobutyric acid receptor subunit beta-3 (GABRB3) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
ECA5 antibody, GABA A receptor beta 3 subunit antibody, GABA A receptor subunit beta 3 antibody, GABA alpha receptor beta 3 subunit antibody, GABA alpha receptor beta-2 subunit antibody, GABA(A) receptor beta 3 subunit antibody, GABA(A) receptor subunit beta 3 antibody, GABA(A) receptor subunit beta-3 antibody, GABAA receptor beta 3 subunit antibody, GABAA receptor subunit beta 3 antibody, GABR B3 antibody, GABRB 3 antibody, GABRB3 antibody, Gamma aminobutyric acid (GABA) A receptor beta 3 antibody, Gamma aminobutyric acid A receptor beta 3 antibody, Gamma aminobutyric acid receptor subunit beta 3 antibody, Gamma-aminobutyric acid receptor subunit beta-3 antibody, GBRB3_HUMAN antibody, MGC9051 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human GABRB3 (344-375aa EKTAKAKNDRSKSESNRVDAHGNILLTSLEVH), different from the related mouse and rat sequences by five amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human GABRB3 (344-375aa EKTAKAKNDRSKSESNRVDAHGNILLTSLEVH), different from the related mouse and rat sequences by five amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.