GAD1 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP11228b
Background:
This gene encodes one of several forms of glutamic aciddecarboxylase, identified as a major autoantigen ininsulin-dependent diabetes. The enzyme encoded is responsible forcatalyzing the production of gamma-aminobutyric acid fromL-glutamic acid. A pathogenic role for this enzyme has beenidentified in the human pancreas since it has been identified as anautoantigen and an autoreactive T cell target in insulin-dependentdiabetes. This gene may also play a role in the stiff man syndrome.Deficiency in this enzyme has been shown to lead to pyridoxinedependency with seizures. Alternative splicing of this gene resultsin two products, the predominant 67-kD form and a less-frequent25-kD form.
Other Names:
Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform, GAD1, GAD, GAD67
Gene Name: GAD1 (HGNC:4092)
Gene ID: 2571
Primary Accession: Q99259
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes one of several forms of glutamic aciddecarboxylase, identified as a major autoantigen ininsulin-dependent diabetes. The enzyme encoded is responsible forcatalyzing the production of gamma-aminobutyric acid fromL-glutamic acid. A pathogenic role for this enzyme has beenidentified in the human pancreas since it has been identified as anautoantigen and an autoreactive T cell target in insulin-dependentdiabetes. This gene may also play a role in the stiff man syndrome.Deficiency in this enzyme has been shown to lead to pyridoxinedependency with seizures. Alternative splicing of this gene resultsin two products, the predominant 67-kD form and a less-frequent25-kD form.
Other Names:
Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform, GAD1, GAD, GAD67
Gene Name: GAD1 (HGNC:4092)
Gene ID: 2571
Primary Accession: Q99259
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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