GAD2 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP11118C
Catalog Number: AC-AP11118C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19330
Applications: WB, IHC-P, IF
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19330
Applications: WB, IHC-P, IF
Datasheet
Request Information
Background:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Other Names:
Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65 kDa isoform, GAD2, GAD65
Target/Specificity:
This GAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GAD2.
Antigen Region:
109-138
Antigen Type: Synthetic Peptide
Gene Name: GAD2 (HGNC:4093)
Gene ID: 2572
Primary Accession: Q05329
NCBI Accession: NP_000809.1;NP_001127838.1
Other Accession: Q05683; P48321; P48320; NP_001127838.1; NP_000809.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Other Names:
Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65 kDa isoform, GAD2, GAD65
Target/Specificity:
This GAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GAD2.
Antigen Region:
109-138
Antigen Type: Synthetic Peptide
Gene Name: GAD2 (HGNC:4093)
Gene ID: 2572
Primary Accession: Q05329
NCBI Accession: NP_000809.1;NP_001127838.1
Other Accession: Q05683; P48321; P48320; NP_001127838.1; NP_000809.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review